Ultrasound Device Combined With Clot-Buster Safe for Stroke:-
(UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was
safe for ischemic stroke patients.
The device, which uses UTHealth technology licensed to Cerevast Therapeutics, Inc.,
is placed on the stroke patient's head and delivers ultrasound to enhance the effectiveness of
the clot-busting drug tissue plasminogen activator (tPA).
Unlike the traditional hand-held ultrasound probe that's aimed at a blood clot, the hands-free
device used 18 separate probes and showers the deep areas of the brain where large blood
clots cause severe strokes.
In the first study of its kind, 20 moderately severe ischemic stroke patients (12 men and eight
women, average age 63 years) received intravenous tPA up to 4.5 hours after symptoms
occurred and two hours exposure to 2-MHz pulsed wave transcranial ultrasound.
Researchers reported that 13 (or 65 percent) patients either returned home or to rehabilitation
90 days after the combination treatment. After three months, five of the 20 patients had no
disability from the stroke and one had slight disability.
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